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Yasunobu Okuma Selected Research

4-phenylbutylamine

1/2012Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress.
6/2006Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress.
10/2004Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

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Yasunobu Okuma Research Topics

Disease

6Body Weight (Weight, Body)
12/2006 - 02/2002
5Alzheimer Disease (Alzheimer's Disease)
01/2014 - 03/2003
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2019 - 05/2008
4Brain Ischemia (Cerebral Ischemia)
01/2015 - 10/2002
4Parkinsonian Disorders (Parkinsonism)
01/2012 - 06/2006
4Inflammation (Inflammations)
10/2005 - 02/2002
4Ischemia
11/2004 - 01/2002
3Infections
10/2005 - 02/2002
3Hypoxia (Hypoxemia)
11/2004 - 10/2004
2Brain Injuries (Brain Injury)
01/2015 - 01/2002
2Inborn Urea Cycle Disorders
01/2012 - 10/2004
2Pheochromocytoma
04/2005 - 07/2002
2Neuroblastoma
11/2004 - 10/2004
2Infarction (Infarctions)
10/2004 - 10/2004
2Anorexia
08/2003 - 02/2002
1Autism Spectrum Disorder
01/2016
1Parkinson Disease (Parkinson's Disease)
02/2015
1Carcinoma (Carcinomatosis)
09/2014
1Virus Diseases (Viral Diseases)
01/2012
1Neoplasms (Cancer)
01/2012
1Adenocarcinoma of Lung
01/2010
1Necrosis
03/2008
1Weight Loss (Weight Reduction)
06/2007
1Tauopathies
06/2007
1Edema (Dropsy)
10/2004
1Thalassemia
10/2004
1Cystic Fibrosis (Mucoviscidosis)
10/2004
1Stroke (Strokes)
10/2004
1Sickle Cell Anemia (Hemoglobin S Disease)
10/2004
1Fever (Fevers)
02/2002

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
10/2019 - 10/2004
6LeptinIBA
12/2006 - 02/2002
34-phenylbutyric acid (Buphenyl)FDA Link
02/2015 - 10/2004
34-phenylbutylamineIBA
01/2012 - 10/2004
3Endothelin Receptors (Endothelin Receptor)IBA
01/2012 - 06/2006
2Amyloid (Amyloid Fibrils)IBA
01/2014 - 03/2010
2Ligases (Synthetase)IBA
01/2014 - 01/2012
2UbiquitinIBA
01/2014 - 01/2012
2Fatty Acids (Saturated Fatty Acids)IBA
01/2012 - 10/2004
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
05/2008 - 12/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2008 - 10/2004
2Messenger RNA (mRNA)IBA
11/2004 - 01/2002
2InterleukinsIBA
08/2003 - 02/2002
1NeuroliginsIBA
01/2016
1naphthaleneIBA
02/2015
1AmphiregulinIBA
01/2015
1Epidermal Growth Factor (EGF)IBA
01/2015
1EpiregulinIBA
01/2015
1Tretinoin (Retinoic Acid)FDA LinkGeneric
09/2014
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2012
1Casein Kinase II (Casein Kinase 2)IBA
01/2012
1Amyloid beta-PeptidesIBA
03/2010
1hexanoic acid (hexanoate)IBA
01/2010
1CeramidasesIBA
01/2010
1N- (7- (4- nitrobenzo- 2- oxa- 1,3- diazole))- 6- aminocaproyl sphingosineIBA
01/2010
1Tyrosine Kinase InhibitorsIBA
01/2010
1herbimycinIBA
01/2010
1SphingosineIBA
01/2010
1GenisteinIBA
01/2010
1N- 4- nitrobenzo- 2- oxa- 1,3- diazoleaminocaproyl sphingosylphosphorylcholineIBA
01/2010
1ceramide kinaseIBA
01/2010
1CaspasesIBA
03/2008
1RotenoneIBA
06/2007
1CystatinsIBA
10/2005
1Arachidonic Acid (Vitamin F)IBA
04/2005
1Indicators and Reagents (Reagents)IBA
04/2005
1oxophenylarsine (phenylarsine oxide)IBA
04/2005
1interleukin 20 (IL-20)IBA
11/2004
1Endoplasmic Reticulum Chaperone BiPIBA
11/2004
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
10/2004
1Caspase 12IBA
10/2004
1Free Radical ScavengersIBA
10/2004
1EdaravoneIBA
10/2004
1CytokinesIBA
03/2003
1ElementsIBA
10/2002
1Cyclic AMP (AMP, Cyclic)IBA
10/2002
1Carrier Proteins (Binding Protein)IBA
10/2002
1Pharmaceutical PreparationsIBA
09/2002
1Janus KinasesIBA
09/2002
1Tyrosine (L-Tyrosine)FDA Link
07/2002
1Prostaglandins FIBA
07/2002
1ProstaglandinsIBA
07/2002
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
07/2002
1Vanadates (Orthovanadate)IBA
07/2002
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2002
1salicylhydroxamic acid (SHAM)IBA
01/2002
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
01/2002

Therapy/Procedure

1Therapeutics
01/2015